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Sadish Kumar Shanmugam

Sadish Kumar Shanmugam

ITS College of Pharmacy, India

Title: Turbinaria ornata – A marine algal drug treasure

Biography

Biography: Sadish Kumar Shanmugam

Abstract

For the past few decades, compounds from Marine algae have been gaining importance due to the vast chemical diversity. In our continuous research on algae, scientific data and traditional claims prompted us to investigate on the brown alga Turbinaria ornata (Family: Sargassaceae).  The Cyclohexane, Ethyl acetate and Methanolic extracts of Turbinaria ornata were subjected to wide pharmacological screening. Among the extracts, Cyclohexane exhibited cholinomimetic activity by inhibiting the Cholinesterase significantly at P<0.01 in the presence of acetyl choline, Ethyl acetate extract possessed antifungal activity with the MIC of 500 mcg/mL concentration and Methanolic extract showed the highest in vitro DPPH free radical scavenging activity (70.78%) which was comparable to Ascorbic acid, a positive control (78.16%). Also it showed significant anti diabetic activity against Streptozotocin and anti obesity activity against Atorvastatin (P<0.001).

So it is very clear that the brown alga has beneficial effects on oxidative stress, microbes, blood glucose levels, cholesterol level, HDL, LDL, body weight due to presence of its chemical constituents like Gallic acid, Quercetin, Oxygenated Steroids and Glycosides which were identified by various parameters.
Thus Turbinaria ornata proved to be a rich source of potential compounds for further research.