R M Ezhilarasi and S Mahalakshmi
Guru Nanak College, India
Title: Microwave assisted synthesis and characterization of pyrazoline derivatives from chalcones and (4-fluorophenylthio) acetic acid hydrazide
Biography
Biography: R M Ezhilarasi and S Mahalakshmi
Abstract
Pyrazolines are well known important bioorganic molecules. Some new pyrazolines were synthesized by the cyclocondensation of chalcones derived from substituted acetophenone and substituted benzaldehyde with (4-fluorophenylthio) acetic acid hydrazide. Cycocondensation was carried out by refluxing glacial acetic acid solution of reactants with a catalytic amount of polyphosphoric acid and also by subjecting the same reaction mixture to MWI. Both the reactions gave the same products with a yield of 65-70%. MWI required lesser reaction time for the completion of the reaction. Products synthesized were characterized by spectral data.
