Sergey Altarev
Research Institute for Complex Issues of Cardiovascular Diseases, Russian Federation
Title: Clinicians’ motivations to actively participate in industry-sponsored clinical trials
Biography
Biography: Sergey Altarev
Abstract
Aim: The aim of the study was to elaborate on motivational profile of doctors actively engaged in industry-sponsored clinical research. Methods: The study participants comprised clinicians of 4 hospitals from the different parts of Russia. The doctors were invited to complete a questionnaire comprising questions on the number of simultaneously managed clinical trial patients during the previous year and on what attracts them to take part in clinical research. Answers to the latter were summarized into 9 different motivational factors. We conducted a factor and a discriminant analyses to describe the relationship between motivation factors and doctors’ engagement in clinical trials. Results: The factor analysis allowed us to reduce the number of motivational factors to 4 groups of factors (Bartlett's Test’s of Sphericity p=0.038). The first one included having new responsibilities and liking the investigational process per se, the second financial aspect and being not independent, the third being able to travel and to communicate with people, and the fourth having scientific/professional interest and having an opportunity to help patients. Discriminant analysis was applied to describe the relationship between each of the 4 groups of factors and the number of simultaneously managed clinical trial patients during the previous year. The final model included only Factor 4 (Wilks' Lambda=0.806, p=0.002) with area under the curve of 0.712 (p=0.013). Conclusions: The analysis of doctors’ motivations to take part in clinical trials showed that only the desire to help patients and/or having professional/scientific interest in a trial could increase doctors’ engagement in clinical research.