Day 2 :
Seoul National University, Korea
Time : 10:00-10:30 AM
Young-Ger Suh is a Professor of College of Pharmacy, Seoul National University, Korea. He graduated from Seoul National University with a B.S. degree in Pharmacy in 1975 and received Ph.D. degree from University of Pittsburgh in 1987. Currently, he is a President of Korean Society of Organic Synthesis, a full member of The Korean Academy of Science and Technology, a Fellow of Asian Federation for Medicinal Chemistry, and a Vice President of The Korean Federation of Science and Technology Societies. He has published more than 150 papers in reputed journals and presented more than 200 papers at Scientific Meetings.
Hypoxia is a special feature occurring in vascular diseases and induces the transcriptional genes involved in glycolysis, haematopoiesis, invasion and angiogenesis. Hypoxia-inducible factor-1α (HIF-1α), which is a key mediator of angiogenesis, is overexpressed under hypoxic condition and transcripts various genes. Our initial studies conﬁrmed that deguelin, a rotenoid, disrupts ATP binding to hsp90 and consequently induces destabilization of HIF-1α. We have identified novel hsp90 inhibitors through the SAR studies including structure truncation of deguelin. The new hsp90 inhibitors exhibited excellent antiproliferative and antiangiogenic activities, which are applicable for treatment of the angiogenesis-related ocular diseases. In particular, two representative hsp90 inhibitors exhibited suppression of hypoxia-mediated retinal neovascularization and vascular leakage in diabetic retina. They effectively suppressed expression of target genes of HIF-1α including vegfa in the retina of oxygen-induced retinopathy (OIR) mice, but do not induce definite toxicity. We will report our recent progress on the development of antiangiogenic agent with detailed discussions.
Northampton University, UK
Time : 10:30-11:00 AM
Dr Aref Alabed, a competent manager with extensive years of experience in leading arnmedical facility. He implements policies and procedures, focusing on the development of the organization by fulfilling the mission, vision and goals. The objectives are his top priorities. Dr Aref is a Dentist, holding an MBA with Merit from Northampton university in UK, he is the Founder & CEO for the International Medical Training Academy in London, and an international relations Consultant for the Largest Chain of pharmacies in Jordan with more than 100 Pharmacies today (Dawacom). He was the Marketing director and built the Marketing department from scratch.
There is no doubt that patient counselling has a positive and significant impact on the patient's knowledge when visiting a pharmacy. Research proved that 8 out of 10 patients cannot remember what the doctor told them about their prescribed medication! What is it? How should it be taken? Also what if the patient forgot to tell the Doctor about the medication they take at home? This would then result in a drug-drug interaction with the new prescribed medication! Can you imagine that only 20% of what you tell the patient is scientific knowledge, the other 80% is all about counselling, empathy and education with the patient! Pharmacists do not focus on these skills during their university level because they are busy with developing their scientific knowledge! We also must bear in mind that the majority of patients are not aware that it is the pharmacist who is responsible in giving them all information required with regard to their medication, they think it is only the Doctor’s job. For that reason the pharmacist must always start to counsel the patient, unless the patient shows previous knowledge! During a typical working day for a pharmacist it’s impossible to counsel all the patients, therefore counselling in a written form will definitely come in handy, of course it is not to replace the face to face counselling, it is still very important! Whether it’s through face to face counselling or through a written form at the end of the day all pharmacists should strive for one goal when counselling patients: which is to ensure that patients are well informed about the proper use of their medications.